Homo sapiens Gene: GGT6 | |||||||||||||
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Summary | |||||||||||||
InnateDB Gene | IDBG-18985.6 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | GGT6 | ||||||||||||
Gene Name | gamma-glutamyltransferase 6 | ||||||||||||
Synonyms | |||||||||||||
Species | Homo sapiens | ||||||||||||
Ensembl Gene | ENSG00000167741 | ||||||||||||
Encoded Proteins |
gamma-glutamyltransferase 6
gamma-glutamyltransferase 6
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Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
GGT6 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM, Oct 2008] |
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Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome 17:4556927-4560818 | ||||||||||||
Strand | Reverse strand | ||||||||||||
Band | p13.2 | ||||||||||||
Transcripts |
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Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||
NETPATH | |||||||||||||
REACTOME |
Glutathione synthesis and recycling pathway
Glutathione conjugation pathway
Aflatoxin activation and detoxification pathway
Phase II conjugation pathway
Metabolism pathway
Biological oxidations pathway
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KEGG |
Cyanoamino acid metabolism pathway
Taurine and hypotaurine metabolism pathway
Glutathione metabolism pathway
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INOH | |||||||||||||
PID NCI | |||||||||||||
Cross-References | |||||||||||||
SwissProt | |||||||||||||
TrEMBL | B4DPG6 | ||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 124975 | ||||||||||||
UniGene | Hs.130749 Hs.606318 | ||||||||||||
RefSeq | NM_001122890 NM_001288702 NM_001288703 NM_001288704 NM_153338 | ||||||||||||
HUGO | HGNC:26891 | ||||||||||||
OMIM | 612341 | ||||||||||||
CCDS | CCDS11047 CCDS45582 CCDS73942 | ||||||||||||
HPRD | 08293 | ||||||||||||
IMGT | |||||||||||||
EMBL | AC118754 AK298329 | ||||||||||||
GenPept | BAG60578 | ||||||||||||
RNA Seq Atlas | 124975 | ||||||||||||