InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Il19

Summary

InnateDB Protein

IDBP-190665.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Il19

Protein Name

interleukin 19

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000016668

InnateDB Gene

IDBG-190663 (Il19)

Protein Structure

UniProt Annotation

Function

May play some important roles in inflammatory responses. Up-regulates IL-6 and TNF-alpha and induces apoptosis. {ECO:0000269PubMed:12370360}.

Subcellular Localization

Secreted.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005125	cytokine activity

Biological Process

GO:0006915	apoptotic process
GO:0042226	interleukin-6 biosynthetic process
GO:0045087	innate immune response (InnateDB)
GO:0072593	reactive oxygen species metabolic process
GO:2001235	positive regulation of apoptotic signaling pathway
GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
GO:2001244	positive regulation of intrinsic apoptotic signaling pathway