Version 5.4
Mus musculus Protein: Acp2
Summary
InnateDB Protein IDBP-190865.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Acp2
Protein Name acid phosphatase 2, lysosomal
Synonyms Acp-2; LAP;
Species Mus musculus
Ensembl Protein ENSMUSP00000002172
InnateDB Gene IDBG-190861 (Acp2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Lysosome membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}; Lumenal side {ECO:0000250}. Lysosome lumen {ECO:0000250}. Note=The soluble form arises by proteolytic processing of the membrane-bound form. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003993 acid phosphatase activity
Biological Process
GO:0001501 skeletal system development
GO:0007040 lysosome organization
GO:0016311 dephosphorylation
Cellular Component
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0043202 lysosomal lumen
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:87882
InterPro IPR000560 Histidine phosphatase superfamily, clade-2
IPR029033 Histidine phosphatase superfamily
PFAM PF00328
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P24638
PhosphoSite PhosphoSite-P24638
TrEMBL
UniProt Splice Variant
Entrez Gene 11432
UniGene Mm.45570
RefSeq NP_031413
MGI ID
MGI Symbol Acp2
OMIM
CCDS CCDS16427
HPRD
IMGT
EMBL BC023343 X57199
GenPept AAH23343 CAA40485

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca