InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Zfhx3

Summary

InnateDB Protein

IDBP-191006.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Zfhx3

Protein Name

zinc finger homeobox 3

Synonyms

A230102L03Rik; Atbf1; mKIAA4228; WBP9;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000044612

InnateDB Gene

IDBG-191004 (Zfhx3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003779	actin binding
GO:0008270	zinc ion binding
GO:0019899	enzyme binding
GO:0043565	sequence-specific DNA binding
GO:0044212	transcription regulatory region DNA binding
GO:0046872	metal ion binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006355	regulation of transcription, DNA-templated
GO:0007010	cytoskeleton organization
GO:0007050	cell cycle arrest
GO:0007420	brain development
GO:0045662	negative regulation of myoblast differentiation
GO:0045663	positive regulation of myoblast differentiation
GO:0045664	regulation of neuron differentiation
GO:0045892	negative regulation of transcription, DNA-templated

Cellular Component

GO:0005634	nucleus
GO:0005667	transcription factor complex
GO:0005737	cytoplasm
GO:0005739	mitochondrion

Protein Structure and Domains

PDB ID

MGI:99948

InterPro

IPR001356 Homeobox domain
IPR003604 Zinc finger, U1-type
IPR007087 Zinc finger, C2H2
IPR009057 Homeodomain-like
IPR013992 Adenylate cyclase-associated CAP, N-terminal
IPR015880 Zinc finger, C2H2-like

PFAM

PF00046
PF00096
PF01213

PRINTS

PIRSF

SMART

SM00389
SM00451
SM00355

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite