Version 5.4
Mus musculus Protein: Atp1b2
Summary
InnateDB Protein IDBP-191114.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Atp1b2
Protein Name ATPase, Na+/K+ transporting, beta 2 polypeptide
Synonyms Amog; Atpb-2;
Species Mus musculus
Ensembl Protein ENSMUSP00000047353
InnateDB Gene IDBG-191112 (Atp1b2)
Protein Structure
UniProt Annotation
Function This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-2 subunit is not known.Mediates cell adhesion of neurons and astrocytes, and promotes neurite outgrowth.
Subcellular Localization Cell membrane; Single-pass type II membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006813 potassium ion transport
GO:0006814 sodium ion transport
GO:0007155 cell adhesion
Cellular Component
GO:0005737 cytoplasm
GO:0005890 sodium:potassium-exchanging ATPase complex
GO:0016324 apical plasma membrane
Protein Structure and Domains
PDB ID MGI:88109
InterPro IPR000402 Sodium/potassium-transporting ATPase subunit beta
PFAM PF00287
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P14231
PhosphoSite PhosphoSite-P14231
TrEMBL Q3UR55
UniProt Splice Variant
Entrez Gene 11932
UniGene Mm.427142
RefSeq NP_038201
MGI ID
MGI Symbol Atp1b2
OMIM
CCDS CCDS24898
HPRD
IMGT
EMBL AK141786 BC042467 BC058763 CH466601 M60897 X16645 X56007
GenPept AAH42467 AAH58763 BAE24833 CAA34638 CAA39482 EDL10509

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca