InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ap1g1

Summary

InnateDB Protein

IDBP-191482.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Ap1g1

Protein Name

adaptor protein complex AP-1, gamma 1 subunit

Synonyms

AA409002; Adtg; AU041323; AW551707; D8Ertd374e;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000090844

InnateDB Gene

IDBG-191480 (Ap1g1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.

Experimentally validated
Total	18 [view]
Protein-Protein	18 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	25 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005488	binding
GO:0005515	protein binding
GO:0008565	protein transporter activity
GO:0017137	Rab GTPase binding
GO:0019894	kinesin binding
GO:0030742	GTP-dependent protein binding

Biological Process

GO:0006886	intracellular protein transport
GO:0015031	protein transport
GO:0016192	vesicle-mediated transport
GO:0035646	endosome to melanosome transport
GO:0043323	positive regulation of natural killer cell degranulation
GO:0045954	positive regulation of natural killer cell mediated cytotoxicity
GO:0090160	Golgi to lysosome transport

Cellular Component

GO:0005737	cytoplasm
GO:0005794	Golgi apparatus
GO:0005802	trans-Golgi network
GO:0016020	membrane
GO:0030117	membrane coat
GO:0030131	clathrin adaptor complex
GO:0030136	clathrin-coated vesicle
GO:0043231	intracellular membrane-bounded organelle
GO:0048471	perinuclear region of cytoplasm
GO:0055037	recycling endosome

Protein Structure and Domains

PDB ID

MGI:101919

InterPro

IPR002553 Clathrin/coatomer adaptor, adaptin-like, N-terminal
IPR008152 Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain
IPR008153 Clathrin adaptor, gamma-adaptin, appendage
IPR013041 Coatomer/clathrin adaptor appendage, Ig-like subdomain
IPR016024 Armadillo-type fold
IPR017107 Adaptor protein complex AP-1, gamma subunit

PFAM

PF01602
PF02883

PRINTS

PIRSF

PIRSF037094

SMART

SM00809

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt