Mus musculus Protein: Bcar3
Summary
InnateDB Protein IDBP-191669.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Bcar3
Protein Name breast cancer anti-estrogen resistance 3
Synonyms AI131758; AND-34;
Species Mus musculus
Ensembl Protein ENSMUSP00000029766
InnateDB Gene IDBG-191667 (Bcar3)
Protein Structure
UniProt Annotation
Function May act as an adapter protein and couple activated growth factor receptors to signaling molecules that regulate src kinase activity and promote cell migration. {ECO:0000269PubMed:10896938, ECO:0000269PubMed:12517963}.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed in B-cells. {ECO:0000269PubMed:10438950, ECO:0000269PubMed:12517963}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 46 interaction(s) predicted by orthology.
Predicted by orthology
Total 46 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
Biological Process
GO:0002089 lens morphogenesis in camera-type eye
GO:0007264 small GTPase mediated signal transduction
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0043087 regulation of GTPase activity
Cellular Component
GO:0005622 intracellular
Protein Structure and Domains
PDB ID MGI:1352501
InterPro IPR000980 SH2 domain
IPR001895 Guanine-nucleotide dissociation stimulator CDC25
IPR023578 Ras guanine nucleotide exchange factor, domain
PFAM PF00017
PF14633
PF00617
PRINTS PR00401
PIRSF
SMART SM00252
SM00147
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9QZK2
PhosphoSite PhosphoSite-Q9QZK2
TrEMBL
UniProt Splice Variant
Entrez Gene 29815
UniGene Mm.45815
RefSeq NP_038895
MGI ID
MGI Symbol Bcar3
OMIM
CCDS CCDS17810
HPRD
IMGT
EMBL AF179566 AK143894 AK165396 BC023930
GenPept AAD53182 AAH23930 BAE25587 BAE38160