InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Xrn1

Summary

InnateDB Protein

IDBP-191745.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Xrn1

Protein Name

5'-3' exoribonuclease 1

Synonyms

Dhm2; exo; mXrn1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000034981

InnateDB Gene

IDBG-191743 (Xrn1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.

Predicted by orthology
Total	31 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0004527	exonuclease activity
GO:0005515	protein binding
GO:0008409	5'-3' exonuclease activity
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000956	nuclear-transcribed mRNA catabolic process
GO:0016075	rRNA catabolic process
GO:0071028	nuclear mRNA surveillance
GO:0071044	histone mRNA catabolic process
GO:0090305	nucleic acid phosphodiester bond hydrolysis

Cellular Component

GO:0000932	cytoplasmic mRNA processing body
GO:0005622	intracellular
GO:0005794	Golgi apparatus
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0045111	intermediate filament cytoskeleton