Version 5.4
Mus musculus Protein: Col16a1
Summary
InnateDB Protein IDBP-191871.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Col16a1
Protein Name collagen, type XVI, alpha 1
Synonyms 2700007F12Rik; A530052M23Rik; AI838662; CA1F;
Species Mus musculus
Ensembl Protein ENSMUSP00000035802
InnateDB Gene IDBG-191869 (Col16a1)
Protein Structure
UniProt Annotation
Function Involved in mediating cell attachment and inducing integrin-mediated cellular reactions, such as cell spreading and alterations in cell morphology. {ECO:0000250UniProtKB:Q07092}.
Subcellular Localization Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in most tissues examined with highest levels of expression observed in heart. Strongly expressed in cortical and medullar regions of kidney and more weakly expressed in lung. Also detected in the ciliary muscle of the eye, on the serosa layer lining the muscularis externa of intestinal tissue, and in the perimysium membrane lining both the cardiac muscle bundle and the smooth muscle tissue of the small intestine. Strongly stained in particulate or granular structures. Not detected in brain or skeletal muscle. {ECO:0000269PubMed:8650669}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005178 integrin binding
GO:0005515 protein binding
Biological Process
GO:0007155 cell adhesion
GO:0071230 cellular response to amino acid stimulus
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0005581 collagen trimer
Protein Structure and Domains
PDB ID MGI:1095396
InterPro IPR001791 Laminin G domain
IPR008160 Collagen triple helix repeat
IPR008985 Concanavalin A-like lectin/glucanases superfamily
PFAM PF00054
PF02210
PF01391
PRINTS
PIRSF
SMART SM00210
SM00282
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BLX7
PhosphoSite PhosphoSite-Q8BLX7
TrEMBL A3KFV2
UniProt Splice Variant
Entrez Gene 107581
UniGene Mm.41860
RefSeq NP_082542
MGI ID
MGI Symbol Col16a1
OMIM
CCDS CCDS38889
HPRD
IMGT
EMBL AK012212 AK040971 AL606925
GenPept BAB28100 BAC30765 CAM45907

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca