Version 5.4
Mus musculus Protein: Ung
Summary
InnateDB Protein IDBP-192234.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ung
Protein Name uracil DNA glycosylase
Synonyms UNG1; UNG2;
Species Mus musculus
Ensembl Protein ENSMUSP00000031587
InnateDB Gene IDBG-192232 (Ung)
Protein Structure
UniProt Annotation
Function Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
Subcellular Localization Isoform 1: Mitochondrion.Isoform 2: Nucleus.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004844 uracil DNA N-glycosylase activity
Biological Process
GO:0006281 DNA repair
GO:0006284 base-excision repair
GO:0016446 somatic hypermutation of immunoglobulin genes
GO:0016447 somatic recombination of immunoglobulin gene segments
GO:0043066 negative regulation of apoptotic process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID MGI:109352
InterPro IPR002043 Uracil-DNA glycosylase
IPR005122 Uracil-DNA glycosylase-like
PFAM PF03167
PRINTS
PIRSF
SMART SM00986
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P97931
PhosphoSite PhosphoSite-P97931
TrEMBL D3Z1G1
UniProt Splice Variant
Entrez Gene 22256
UniGene Mm.1393
RefSeq NP_001035781
MGI ID
MGI Symbol Ung
OMIM
CCDS CCDS39221
HPRD
IMGT
EMBL AC122282 AC129080 AF174485 AK146178 BC011039 BC052853 CH466529 U55040 U55041 X99018 Y08975
GenPept AAB39511 AAC53197 AAF76936 AAH11039 AAH52853 BAE26956 CAA67489 CAA70168 EDL19920

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca