InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Srgap1

Summary

InnateDB Protein

IDBP-193099.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Srgap1

Protein Name

SLIT-ROBO Rho GTPase activating protein 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000080389

InnateDB Gene

IDBG-193095 (Srgap1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005100	Rho GTPase activator activity
GO:0005515	protein binding
GO:0017048	Rho GTPase binding

Biological Process

GO:0007165	signal transduction
GO:0007266	Rho protein signal transduction
GO:0016477	cell migration
GO:0032321	positive regulation of Rho GTPase activity

Cellular Component

GO:0005622

intracellular

Protein Structure and Domains

PDB ID

MGI:2152936

InterPro

IPR000198 Rho GTPase-activating protein domain
IPR001060 FCH domain
IPR001452 SH3 domain
IPR004216 L-fucose/L-arabinose isomerase, C-terminal
IPR008936 Rho GTPase activation protein
IPR011511 Variant SH3 domain

PFAM

PF00620
PF00611
PF00018
PF14604
PF07653

PRINTS

PR00452

PIRSF

SMART

SM00324
SM00055
SM00326

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt