Version 5.4
Mus musculus Gene: Srgap1
Summary
InnateDB Gene IDBG-193095.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Srgap1
Gene Name SLIT-ROBO Rho GTPase activating protein 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000020121
Encoded Proteins
IDBP-193097
SLIT-ROBO Rho GTPase activating protein 1
IDBP-193099
SLIT-ROBO Rho GTPase activating protein 1
IDBP-538659
SLIT-ROBO Rho GTPase activating protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000196935:
Gene Information
Type Protein coding
Genomic Location Chromosome 10:121780991-122047315
Strand Reverse strand
Band D2
Transcripts
ENSMUST00000020322 ENSMUSP00000020322
ENSMUST00000081688 ENSMUSP00000080389
ENSMUST00000161996
ENSMUST00000161156 ENSMUSP00000125109
ENSMUST00000162710
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005100 Rho GTPase activator activity
GO:0005515 protein binding
GO:0017048 Rho GTPase binding
Biological Process
GO:0007165 signal transduction
GO:0007266 Rho protein signal transduction
GO:0016477 cell migration
GO:0032321 positive regulation of Rho GTPase activity
Cellular Component
GO:0005622 intracellular
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000196935
View Gene Order
ENSBTAG00000011892
Not yet available
Pathways
NETPATH
REACTOME
REACT_221567
Signaling by Robo receptor pathway
REACT_206918
Signaling by Rho GTPases pathway
REACT_253889
Inactivation of Cdc42 and Rac pathway
REACT_261444
Axon guidance pathway
REACT_210090
Rho GTPase cycle pathway
REACT_188576
Developmental Biology pathway
REACT_188257
Signal Transduction pathway
KEGG
mmu04360
Axon guidance pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_11051
Rho GTPase cycle pathway
REACT_19342
Inactivation of Cdc42 and Rac pathway
REACT_19351
Signaling by Robo receptor pathway
REACT_111045
Developmental Biology pathway
REACT_11044
Signaling by Rho GTPases pathway
REACT_18266
Axon guidance pathway
REACT_111102
Signal Transduction pathway
KEGG
hsa04360
Axon guidance pathway
INOH
PID NCI
rhoa_reg_pathway
Regulation of RhoA activity
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.288698 Mm.403674
RefSeq NM_001081037 NM_001242411 XM_006513140
OMIM
CCDS CCDS36075 CCDS56751
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca