InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Sox14

Summary

InnateDB Protein

IDBP-193152.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sox14

Protein Name

SRY-box containing gene 14

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000091310

InnateDB Gene

IDBG-193150 (Sox14)

Protein Structure

UniProt Annotation

Function

Acts as a negative regulator of transcription. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00267}.

Disease Associations

Tissue Specificity

Highly expressed in developing brain and spinal cord. {ECO:0000269PubMed:10677261}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003682	chromatin binding
GO:0043565	sequence-specific DNA binding
GO:0046982	protein heterodimerization activity

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006366	transcription from RNA polymerase II promoter
GO:0007601	visual perception
GO:0009649	entrainment of circadian clock
GO:0045892	negative regulation of transcription, DNA-templated
GO:2001222	regulation of neuron migration