Version 5.4
Mus musculus Gene: Sox14
Summary
InnateDB Gene IDBG-193150.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sox14
Gene Name SRY-box containing gene 14
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000053747
Encoded Proteins
IDBP-193152
SRY-box containing gene 14
IDBP-787978
SRY (sex determining region Y)-box 14
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168875:
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene are suggested to be responsible for the limb defects associated with blepharophimosis, ptosis, epicanthus inversus syndrome (BPES) and Mobius syndrome. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:99874106-99876170
Strand Reverse strand
Band E3.3
Transcripts
ENSMUST00000054819 ENSMUSP00000091310
ENSMUST00000183065 ENSMUSP00000138239
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003682 chromatin binding
GO:0043565 sequence-specific DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0007601 visual perception
GO:0009649 entrainment of circadian clock
GO:0045892 negative regulation of transcription, DNA-templated
GO:2001222 regulation of neuron migration
Cellular Component
GO:0044798 nuclear transcription factor complex
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000168875
View Gene Order
Cross-References
SwissProt Q04892
TrEMBL Q3UUP3 Q497H4 Q5XJE3 Q6NSR1 Q7TNS9
UniProt Splice Variant
Entrez Gene 20669
UniGene Mm.261595
RefSeq NM_011440
OMIM
CCDS CCDS57695
HPRD
IMGT
MGI ID MGI:98362
MGI Symbol Sox14
EMBL AF182357 AF193435 AF193437 AK138208 BC055767 BC069948 BC083360 BC100555 CH466560 Z18963
GenPept AAF19353 AAF62396 AAF62397 AAH55767 AAH69948 AAH83360 AAI00556 BAE23582 CAA79488 EDL21023
RNA Seq Atlas 20669

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca