InnateDB Protein
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IDBP-19390.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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OTOA
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Protein Name
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otoancorin
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000373609
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InnateDB Gene
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IDBG-19380 (OTOA)
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Protein Structure
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Function |
May act as an adhesion molecule.
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Subcellular Localization |
Apical cell membrane {ECO:0000305}; Lipid- anchor, GPI-anchor {ECO:0000305}; Extracellular side {ECO:0000305}. Secreted, extracellular space, extracellular matrix {ECO:0000305}. Note=At the interface between the apical surface of the epithelia and the overlying acellular gel of the tectorial and otoconial membranes. {ECO:0000250}.
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Disease Associations |
Deafness, autosomal recessive, 22 (DFNB22) [MIM:607039]: A form of non-syndromic sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. {ECO:0000269PubMed:11972037}. Note=The disease is caused by mutations affecting the gene represented in this entry.
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q7RTW8
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PhosphoSite |
PhosphoSite-Q7RTW8
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TrEMBL |
B4DZ38
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UniProt Splice Variant |
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Entrez Gene |
146183
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UniGene |
Hs.408336
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RefSeq |
NP_733764
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HUGO |
HGNC:16378
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OMIM |
607038
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CCDS |
CCDS32403
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HPRD |
06126
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IMGT |
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EMBL |
AC092719
AK057335
AK093062
AK125840
AK302733
BC129992
BC129993
BK000099
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GenPept |
AAI29993
AAI29994
BAC04040
BAG54255
BAG63950
DAA00022
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