Mus musculus Protein: Sesn2
Summary
InnateDB Protein IDBP-194026.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sesn2
Protein Name sestrin 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000030724
InnateDB Gene IDBG-194024 (Sesn2)
Protein Structure
UniProt Annotation
Function Involved in the reduction of peroxiredoxins. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0001932 regulation of protein phosphorylation
GO:0006635 fatty acid beta-oxidation
GO:0006914 autophagy
GO:0007005 mitochondrion organization
GO:0009749 response to glucose
GO:0032042 mitochondrial DNA metabolic process
GO:0032868 response to insulin
GO:0042593 glucose homeostasis
GO:0043491 protein kinase B signaling
GO:0046323 glucose import
GO:0070328 triglyceride homeostasis
GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis
GO:1901031 regulation of response to reactive oxygen species
GO:2000479 regulation of cAMP-dependent protein kinase activity
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:2651874
InterPro IPR006730 Sestrin
IPR029032 AhpD-like
PFAM PF04636
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P58043
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 230784
UniGene Mm.400799
RefSeq NP_659156
MGI ID
MGI Symbol Sesn2
OMIM
CCDS CCDS18726
HPRD
IMGT
EMBL BC005672
GenPept AAH05672