InnateDB Protein
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IDBP-194029.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Anapc13
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Protein Name
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anaphase promoting complex subunit 13
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Synonyms
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1810004D07Rik; APC13; SWM1;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000039761
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InnateDB Gene
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IDBG-194027 (Anapc13)
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Protein Structure
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Function |
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated |
Total |
10
[view]
|
Protein-Protein |
10
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
16 [view]
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|
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1916260
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InterPro |
IPR008401
Apc13p
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PFAM |
PF05839
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8R034
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
69010
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UniGene |
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RefSeq |
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MGI ID |
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MGI Symbol |
Anapc13
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OMIM |
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CCDS |
CCDS40744
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HPRD |
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IMGT |
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EMBL |
AK007332
BC028526
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GenPept |
AAH28526
BAC25171
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