InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Anapc13

Summary

InnateDB Gene

IDBG-194027.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Anapc13

Gene Name

anaphase promoting complex subunit 13

Synonyms

1810004D07Rik; APC13; SWM1

Species

Mus musculus

Ensembl Gene

ENSMUSG00000035048

Encoded Proteins

IDBP-194029

anaphase promoting complex subunit 13

IDBP-789840

anaphase promoting complex subunit 13

IDBP-789841

anaphase promoting complex subunit 13

IDBP-789843

anaphase promoting complex subunit 13

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000129055:
This gene encodes a component of the anaphase promoting complex, a large ubiquitin-protein ligase that controls cell cycle progression by regulating the degradation of cell cycle regulators such as B-type cyclins. The encoded protein is evolutionarily conserved and is required for the integrity and ubiquitin ligase activity of the anaphase promoting complex. Pseudogenes and splice variants have been found for this gene; however, the biological validity of some of the splice variants has not been determined. [provided by RefSeq, Nov 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 9:102626296-102634425

Strand

Forward strand

Band

Transcripts

ENSMUST00000038673	ENSMUSP00000039761
ENSMUST00000190279	ENSMUSP00000140967
ENSMUST00000188398	ENSMUSP00000140325
ENSMUST00000186693	ENSMUSP00000139762
ENSMUST00000190354

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.

Experimentally validated
Total	10 [view]
Protein-Protein	10 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	16 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0007067	mitotic nuclear division
GO:0070979	protein K11-linked ubiquitination

Cellular Component

GO:0005680

anaphase-promoting complex

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000129055

View Gene Order

ENSBTAG00000014461

Not yet available

Pathways

NETPATH

REACTOME

REACT_236645

Class I MHC mediated antigen processing & presentation pathway

REACT_230745

Immune System pathway

REACT_199115

Antigen processing: Ubiquitination & Proteasome degradation pathway

REACT_229531

Adaptive Immune System pathway

KEGG

mmu04120

Ubiquitin mediated proteolysis pathway

mmu04110

Cell cycle pathway

mmu04914

Progesterone-mediated oocyte maturation pathway

mmu04114

Oocyte meiosis pathway

INOH

PID NCI

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

REACT_75842

Antigen processing: Ubiquitination & Proteasome degradation pathway

REACT_75774

Adaptive Immune System pathway

REACT_6900

Immune System pathway

REACT_75820

Class I MHC mediated antigen processing & presentation pathway

KEGG

hsa04110

Cell cycle pathway

hsa04120

Ubiquitin mediated proteolysis pathway

hsa04914

Progesterone-mediated oocyte maturation pathway

hsa04114

Oocyte meiosis pathway

INOH

PID NCI

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

NM_181394 XM_006511806 XM_006511807

OMIM

CCDS

CCDS40744

HPRD

IMGT

MGI ID

MGI Symbol

EMBL

GenPept

RNA Seq Atlas