InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: B4galnt1

Summary

InnateDB Protein

IDBP-194247.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

B4galnt1

Protein Name

beta-1,4-N-acetyl-galactosaminyl transferase 1

Synonyms

4933429D13Rik; Gal-NAc-T; Galgt1; GalNAc-T; GalNAcT; Ggm-2; Ggm2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000006914

InnateDB Gene

IDBG-194245 (B4galnt1)

Protein Structure

UniProt Annotation

Function

Involved in the biosynthesis of gangliosides GM2, GD2 and GA2.

Subcellular Localization

Golgi apparatus membrane; Single-pass type II membrane protein.

Disease Associations

Tissue Specificity

Most abundant in brain, liver, lung, spleen and testis.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003947	(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity
GO:0008376	acetylgalactosaminyltransferase activity
GO:0016758	transferase activity, transferring hexosyl groups

Biological Process

GO:0001574	ganglioside biosynthetic process
GO:0006486	protein glycosylation
GO:0006687	glycosphingolipid metabolic process
GO:0007283	spermatogenesis
GO:0019915	lipid storage
GO:0030259	lipid glycosylation