Version 5.4
| Mus musculus Protein: Ptpn7 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-194350.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Ptpn7 | ||||||||
| Protein Name | protein tyrosine phosphatase, non-receptor type 7 | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000045803 | ||||||||
| InnateDB Gene | IDBG-194348 (Ptpn7) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | May play a role in the regulation of T and B-lymphocyte development and signal transduction. {ECO:0000250}. | ||||||||
| Subcellular Localization | Cytoplasm {ECO:0000269PubMed:20157115}. Cytoplasm, cytoskeleton {ECO:0000269PubMed:20157115}. Note=Oxidized form is preferentially associated with actin cytoskeleton. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Expressed in bone marrow-derived mast cells. {ECO:0000269PubMed:20157115}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:2156893 | ||||||||
| InterPro |
IPR000242
Protein-tyrosine phosphatase, receptor/non-receptor type IPR000387 Protein-tyrosine/Dual specificity phosphatase IPR003595 Protein-tyrosine phosphatase, catalytic IPR008356 Protein-tyrosine phosphatase, KIM-containing IPR029021 Protein-tyrosine phosphatase-like |
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| PFAM |
PF00102
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| PRINTS |
PR00700
PR01778 |
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| PIRSF | |||||||||
| SMART |
SM00194
SM00404 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q8BUM3 | ||||||||
| PhosphoSite | PhosphoSite-Q8BUM3 | ||||||||
| TrEMBL | Q8BX26 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 320139 | ||||||||
| UniGene | Mm.395768 | ||||||||
| RefSeq | NP_796055 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Ptpn7 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS15315 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AK049175 AK083305 BC098475 | ||||||||
| GenPept | AAH98475 BAC33587 BAC38856 | ||||||||