Version 5.4
Mus musculus Protein: Nav1
Summary
InnateDB Protein IDBP-194807.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nav1
Protein Name neuron navigator 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000043803
InnateDB Gene IDBG-194803 (Nav1)
Protein Structure
UniProt Annotation
Function May be involved in neuronal migration. {ECO:0000269PubMed:15797708}.
Subcellular Localization Cytoplasm, cytoskeleton {ECO:0000269PubMed:15797708}. Note=Associates with a subset of microtubule plus ends. Enriched in neuronal growth cones.
Disease Associations
Tissue Specificity Expressed in heart and brain. Present in brain (at protein level). In adult brain, found almost exclusively in areas of secondary neurogenesis from the hippocampus and the subventricular zone. {ECO:0000269PubMed:15797708}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0017111 nucleoside-triphosphatase activity
Biological Process
GO:0001578 microtubule bundle formation
GO:0001764 neuron migration
GO:0008152 metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005874 microtubule
GO:0015630 microtubule cytoskeleton
Protein Structure and Domains
PDB ID MGI:2183683
InterPro IPR003593 AAA+ ATPase domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM
PRINTS
PIRSF
SMART SM00382
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8CH77
PhosphoSite PhosphoSite-Q8CH77
TrEMBL
UniProt Splice Variant
Entrez Gene 215690
UniGene Mm.475259
RefSeq XP_006529435
MGI ID
MGI Symbol Nav1
OMIM
CCDS
HPRD
IMGT
EMBL AF307453 AK053255 AK082667 AK122458 AK153742 BC059840 BC080292
GenPept AAH59840 AAH80292 AAO13290 BAC35323 BAC38568 BAC65740 BAE32163

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca