Version 5.4
Mus musculus Gene: Nav1
Summary
InnateDB Gene IDBG-194803.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nav1
Gene Name neuron navigator 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000009418
Encoded Proteins
IDBP-194805
neuron navigator 1
IDBP-194807
neuron navigator 1
IDBP-790101
neuron navigator 1
IDBP-790102
neuron navigator 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134369:
This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known, but it is thought to play a role in in neuronal development and regeneration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:135434580-135607295
Strand Reverse strand
Band E4
Transcripts
ENSMUST00000067414 ENSMUSP00000067241
ENSMUST00000040599 ENSMUSP00000043803
ENSMUST00000190298 ENSMUSP00000140322
ENSMUST00000187311
ENSMUST00000189252 ENSMUSP00000141115
ENSMUST00000190735
ENSMUST00000189362
ENSMUST00000190130
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0017111 nucleoside-triphosphatase activity
Biological Process
GO:0001578 microtubule bundle formation
GO:0001764 neuron migration
GO:0008152 metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005874 microtubule
GO:0015630 microtubule cytoskeleton
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000134369
View Gene Order
ENSBTAG00000021919
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_24
TSLP pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_173437 XM_006529369 XM_006529370 XM_006529371 XM_006529373 XM_006529374 XM_006529378 XM_006529379 XM_006529380
OMIM
CCDS CCDS35720
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca