Version 5.4
Mus musculus Protein: Vps33b
Summary
InnateDB Protein IDBP-194840.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Vps33b
Protein Name vacuolar protein sorting 33B (yeast)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000032749
InnateDB Gene IDBG-194838 (Vps33b)
Protein Structure
UniProt Annotation
Function May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. {ECO:0000250}.
Subcellular Localization Late endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Lysosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Cytoplasmic, peripheral membrane protein associated with late endosomes/lysosomes. Colocalizes in clusters with VIPAS39 at cytoplasmic organelles (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006904 vesicle docking involved in exocytosis
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
GO:0032400 melanosome localization
GO:0032418 lysosome localization
GO:0061025 membrane fusion
GO:0070889 platelet alpha granule organization
Cellular Component
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005770 late endosome
GO:0030897 HOPS complex
GO:0031091 platelet alpha granule
GO:0031902 late endosome membrane
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID MGI:2446237
InterPro IPR001619 Sec1-like protein
PFAM PF00995
PRINTS
PIRSF PIRSF005715
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P59016
PhosphoSite PhosphoSite-P59016
TrEMBL
UniProt Splice Variant
Entrez Gene 233405
UniGene Mm.413509
RefSeq NP_835171
MGI ID
MGI Symbol Vps33b
OMIM
CCDS CCDS39997
HPRD
IMGT
EMBL BC028783 BC034170
GenPept AAH28783 AAH34170

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca