InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ppa2

Summary

InnateDB Protein

IDBP-194959.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ppa2

Protein Name

pyrophosphatase (inorganic) 2

Synonyms

1110013G13Rik; Sid6306;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000029644

InnateDB Gene

IDBG-194957 (Ppa2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Mitochondrion {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	6 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0004427	inorganic diphosphatase activity
GO:0004722	protein serine/threonine phosphatase activity

Biological Process

GO:0006796	phosphate-containing compound metabolic process
GO:0016311	dephosphorylation

Cellular Component

GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:1922026

InterPro

IPR008162 Inorganic pyrophosphatase

PFAM

PF00719

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q91VM9

PhosphoSite

PhosphoSite-Q91VM9

TrEMBL

UniProt Splice Variant

Entrez Gene

74776

UniGene

RefSeq

NP_666253

MGI ID

MGI Symbol

Ppa2

OMIM

CCDS

CCDS17850

HPRD

IMGT

EMBL

AK003660 AK090384 AK143475 BC011417

GenPept

AAH11417 BAB22922 BAC41194 BAE25392