InnateDB Protein
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IDBP-195142.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Hrk
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Protein Name
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harakiri, BCL2 interacting protein (contains only BH3 domain)
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Synonyms
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AI838259; Bid3; DP5; harakiri;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000057532
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InnateDB Gene
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IDBG-195140 (Hrk)
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Protein Structure
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Function |
Promotes apoptosis. {ECO:0000250}.
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Subcellular Localization |
Membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Mitochondrion {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
7 [view]
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Molecular Function |
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Biological Process |
GO:0006915
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apoptotic process
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GO:0032464
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positive regulation of protein homooligomerization
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GO:0043065
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positive regulation of apoptotic process
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GO:0090200
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positive regulation of release of cytochrome c from mitochondria
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Cellular Component |
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PDB ID |
MGI:1201608
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InterPro |
IPR017249
Activator of apoptosis harakiri
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PFAM |
PF15196
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PRINTS |
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PIRSF |
PIRSF037635
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P62816
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
12123
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UniGene |
Mm.428588
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RefSeq |
NP_031571
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MGI ID |
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MGI Symbol |
Hrk
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OMIM |
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CCDS |
CCDS39236
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HPRD |
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IMGT |
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EMBL |
D83698
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GenPept |
BAA12066
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