InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Bdnf

Summary

InnateDB Protein

IDBP-195508.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Bdnf

Protein Name

brain derived neurotrophic factor

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000057989

InnateDB Gene

IDBG-195506 (Bdnf)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005102	receptor binding
GO:0005169	neurotrophin TRKB receptor binding
GO:0005515	protein binding
GO:0008083	growth factor activity

Biological Process

GO:0001657	ureteric bud development
GO:0001662	behavioral fear response
GO:0001666	response to hypoxia
GO:0002544	chronic inflammatory response
GO:0006120	mitochondrial electron transport, NADH to ubiquinone
GO:0007214	gamma-aminobutyric acid signaling pathway
GO:0007399	nervous system development
GO:0007406	negative regulation of neuroblast proliferation
GO:0007411	axon guidance
GO:0007412	axon target recognition
GO:0007611	learning or memory
GO:0007612	learning
GO:0007623	circadian rhythm
GO:0007631	feeding behavior
GO:0008038	neuron recognition
GO:0009416	response to light stimulus
GO:0009642	response to light intensity
GO:0009725	response to hormone
GO:0010996	response to auditory stimulus
GO:0014047	glutamate secretion
GO:0014076	response to fluoxetine
GO:0014823	response to activity
GO:0016358	dendrite development
GO:0019222	regulation of metabolic process
GO:0021675	nerve development
GO:0030516	regulation of axon extension
GO:0031667	response to nutrient levels
GO:0032094	response to food
GO:0032229	negative regulation of synaptic transmission, GABAergic
GO:0033138	positive regulation of peptidyl-serine phosphorylation
GO:0033189	response to vitamin A
GO:0034612	response to tumor necrosis factor
GO:0035864	response to potassium ion
GO:0042490	mechanoreceptor differentiation
GO:0042493	response to drug
GO:0042596	fear response
GO:0043066	negative regulation of apoptotic process
GO:0043523	regulation of neuron apoptotic process
GO:0043524	negative regulation of neuron apoptotic process
GO:0045666	positive regulation of neuron differentiation
GO:0045843	negative regulation of striated muscle tissue development
GO:0046668	regulation of retinal cell programmed cell death
GO:0048167	regulation of synaptic plasticity
GO:0048169	regulation of long-term neuronal synaptic plasticity
GO:0048170	positive regulation of long-term neuronal synaptic plasticity
GO:0048172	regulation of short-term neuronal synaptic plasticity
GO:0048675	axon extension
GO:0048839	inner ear development
GO:0050890	cognition
GO:0051602	response to electrical stimulus
GO:0051965	positive regulation of synapse assembly
GO:0055093	response to hyperoxia
GO:0060079	regulation of excitatory postsynaptic membrane potential
GO:0060548	negative regulation of cell death
GO:0061193	taste bud development
GO:0071356	cellular response to tumor necrosis factor
GO:0071874	cellular response to norepinephrine stimulus
GO:0072347	response to anesthetic
GO:0097484	dendrite extension
GO:1901215	negative regulation of neuron death
GO:1902065	response to L-glutamate
GO:1990089	response to nerve growth factor
GO:1990090	cellular response to nerve growth factor stimulus
GO:1990138	neuron projection extension

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005737	cytoplasm
GO:0005788	endoplasmic reticulum lumen
GO:0008021	synaptic vesicle
GO:0016023	cytoplasmic membrane-bounded vesicle
GO:0030061	mitochondrial crista
GO:0030424	axon
GO:0030425	dendrite
GO:0043025	neuronal cell body
GO:0043195	terminal bouton
GO:0043204	perikaryon
GO:0048471	perinuclear region of cytoplasm