InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Lhx5

Summary

InnateDB Protein

IDBP-195565.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Lhx5

Protein Name

LIM homeobox protein 5

Synonyms

Lim2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000031591

InnateDB Gene

IDBG-195563 (Lhx5)

Protein Structure

UniProt Annotation

Function

Plays an essential role in the regulation of neuronal differentiation and migration during development of the central nervous system.

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0008270	zinc ion binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007267	cell-cell signaling
GO:0021527	spinal cord association neuron differentiation
GO:0021549	cerebellum development
GO:0021702	cerebellar Purkinje cell differentiation
GO:0021766	hippocampus development
GO:0021846	cell proliferation in forebrain
GO:0021879	forebrain neuron differentiation
GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation
GO:0042127	regulation of cell proliferation
GO:0045893	positive regulation of transcription, DNA-templated