InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Myo1a

Summary

InnateDB Protein

IDBP-195836.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Myo1a

Protein Name

myosin IA

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000078540

InnateDB Gene

IDBG-195834 (Myo1a)

Protein Structure

UniProt Annotation

Function

Involved in directing the movement of organelles along actin filaments. {ECO:0000305}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003774	motor activity
GO:0003779	actin binding
GO:0005515	protein binding
GO:0005516	calmodulin binding
GO:0005524	ATP binding

Biological Process

GO:0007605	sensory perception of sound
GO:0008152	metabolic process
GO:0030030	cell projection organization
GO:0030033	microvillus assembly
GO:0051648	vesicle localization

Cellular Component

GO:0005737	cytoplasm
GO:0005902	microvillus
GO:0005903	brush border
GO:0009925	basal plasma membrane
GO:0016323	basolateral plasma membrane
GO:0016324	apical plasma membrane
GO:0016328	lateral plasma membrane
GO:0016459	myosin complex
GO:0030864	cortical actin cytoskeleton
GO:0031941	filamentous actin

Protein Structure and Domains

PDB ID

MGI:107732

InterPro

IPR000048 IQ motif, EF-hand binding site
IPR001609 Myosin head, motor domain
IPR010926 Myosin tail 2
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00612
PF00063
PF06017

PRINTS

PR00193

PIRSF

SMART

SM00015
SM00242

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt