Version 5.4
Mus musculus Gene: Myo1a
Summary
InnateDB Gene IDBG-195834.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Myo1a
Gene Name myosin IA
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000025401
Encoded Proteins
IDBP-195836
myosin IA
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166866:
This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional skeletal muscle myosin-1 (MYH1). Unconventional myosins contain the basic domains characteristic of conventional myosins and are further distinguished from class members by their tail domains. They function as actin-based molecular motors. Mutations in this gene have been associated with autosomal dominant deafness. Alternatively spliced variants have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:127705170-127720887
Strand Forward strand
Band D3
Transcripts
ENSMUST00000079590 ENSMUSP00000078540
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003774 motor activity
GO:0003779 actin binding
GO:0005515 protein binding
GO:0005516 calmodulin binding
GO:0005524 ATP binding
Biological Process
GO:0007605 sensory perception of sound
GO:0008152 metabolic process
GO:0030030 cell projection organization
GO:0030033 microvillus assembly
GO:0051648 vesicle localization
Cellular Component
GO:0005737 cytoplasm
GO:0005902 microvillus
GO:0005903 brush border
GO:0009925 basal plasma membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0016328 lateral plasma membrane
GO:0016459 myosin complex
GO:0030864 cortical actin cytoskeleton
GO:0031941 filamentous actin
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000166866
View Gene Order
ENSBTAG00000014655
Not yet available
Cross-References
SwissProt O88329
TrEMBL
UniProt Splice Variant
Entrez Gene 432516
UniGene Mm.90450
RefSeq NM_001081219 XM_006513859 XM_006513860
OMIM
CCDS CCDS36083
HPRD
IMGT
MGI ID MGI:107732
MGI Symbol Myo1a
EMBL AC160970 AF009960 BC147605 BC147612
GenPept AAC28397 AAI47606 AAI47613
RNA Seq Atlas 432516

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca