InnateDB Protein
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IDBP-196308.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Stmn1
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Protein Name
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stathmin 1
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Synonyms
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19k; Lag; Lap18; Op18; P18; P19; Pig; Pp17; Pp18; Pp19; Pr22; Smn;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000030636
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InnateDB Gene
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IDBG-196306 (Stmn1)
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Protein Structure
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Function |
Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser- 16 may be required for axon formation during neurogenesis (By similarity). Involved in the control of the learned and innate fear. {ECO:0000250, ECO:0000269PubMed:16286011}.
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Subcellular Localization |
Cytoplasm, cytoskeleton.
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Disease Associations |
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Tissue Specificity |
Highly expressed in the lateral nucleus of the amygdala. {ECO:0000269PubMed:16286011}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Experimentally validated |
Total |
4
[view]
|
Protein-Protein |
2
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
1
[view]
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
25 [view]
|
|
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:96739
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InterPro |
IPR000956
Stathmin family
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PFAM |
PF00836
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PRINTS |
PR00345
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PIRSF |
PIRSF002285
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P54227
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PhosphoSite |
PhosphoSite-P54227
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TrEMBL |
Q545B6
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UniProt Splice Variant |
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Entrez Gene |
16765
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UniGene |
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RefSeq |
NP_062615
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MGI ID |
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MGI Symbol |
Stmn1
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OMIM |
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CCDS |
CCDS18772
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HPRD |
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IMGT |
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EMBL |
AK012231
AK012347
AL669982
BC010581
BC031831
BC054396
CH466552
L20256
L20257
L20258
X94915
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GenPept |
AAH10581
AAH31831
AAH54396
BAB28109
BAB28178
CAA64401
EDL30008
EDL30009
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