Version 5.4
Mus musculus Protein: Fuca1
Summary
InnateDB Protein IDBP-197389.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fuca1
Protein Name fucosidase, alpha-L- 1, tissue
Synonyms 0610006A03Rik; 9530055J05Rik; Afuc; Fuca;
Species Mus musculus
Ensembl Protein ENSMUSP00000030434
InnateDB Gene IDBG-197387 (Fuca1)
Protein Structure
UniProt Annotation
Function Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N- acetylglucosamine of the carbohydrate moieties of glycoproteins. {ECO:0000250}.
Subcellular Localization Lysosome {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004560 alpha-L-fucosidase activity
GO:0015928 fucosidase activity
GO:0030246 carbohydrate binding
GO:0042806 fucose binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006004 fucose metabolic process
GO:0016139 glycoside catabolic process
Cellular Component
GO:0005764 lysosome
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:95593
InterPro IPR000933 Glycoside hydrolase, family 29
IPR016286 Alpha-L-fucosidase, metazoa-type
IPR017853 Glycoside hydrolase, superfamily
PFAM PF01120
PRINTS PR00741
PIRSF PIRSF001092
SMART SM00812
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99LJ1
PhosphoSite PhosphoSite-Q99LJ1
TrEMBL
UniProt Splice Variant
Entrez Gene 71665
UniGene Mm.467404
RefSeq NP_077205
MGI ID
MGI Symbol Fuca1
OMIM
CCDS CCDS18794
HPRD
IMGT
EMBL AK002230 AK053323 AK089958 AK151258 AK151361 AK151879 AK151908 AK165604 AL672076 BC003235
GenPept AAH03235 BAB21949 BAC35346 BAC41012 BAE30247 BAE30336 BAE30765 BAE30789 BAE38288 CAM15900

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca