Version 5.4
Mus musculus Protein: Aprt
Summary
InnateDB Protein IDBP-197715.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Aprt
Protein Name adenine phosphoribosyl transferase
Synonyms C85684;
Species Mus musculus
Ensembl Protein ENSMUSP00000006764
InnateDB Gene IDBG-197713 (Aprt)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0002055 adenine binding
GO:0003999 adenine phosphoribosyltransferase activity
GO:0016208 AMP binding
Biological Process
GO:0006166 purine ribonucleoside salvage
GO:0006168 adenine salvage
GO:0007595 lactation
GO:0007625 grooming behavior
GO:0009116 nucleoside metabolic process
GO:0032869 cellular response to insulin stimulus
GO:0044209 AMP salvage
GO:0046083 adenine metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:88061
InterPro IPR000836 Phosphoribosyltransferase domain
IPR005764 Adenine phosphoribosyl transferase
IPR029057 Phosphoribosyltransferase-like
PFAM PF00156
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P08030
PhosphoSite PhosphoSite-P08030
TrEMBL
UniProt Splice Variant
Entrez Gene 11821
UniGene
RefSeq NP_033828
MGI ID
MGI Symbol Aprt
OMIM
CCDS CCDS40503
HPRD
IMGT
EMBL AB033539 AB033540 AC114917 AK002350 AK153201 BC005667 CH466525 M11310 M86439
GenPept AAA37255 AAA37256 AAH05667 BAB22029 BAD95571 BAD95572 BAE31801 EDL11692

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca