Version 5.4
Mus musculus Protein: Myl2
Summary
InnateDB Protein IDBP-197889.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Myl2
Protein Name myosin, light polypeptide 2, regulatory, cardiac, slow
Synonyms MLC-2; MLC-2v; Mlc2v; Mylpc;
Species Mus musculus
Ensembl Protein ENSMUSP00000014080
InnateDB Gene IDBG-197887 (Myl2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm, myofibril, sarcomere, A band {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003785 actin monomer binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0003007 heart morphogenesis
GO:0007507 heart development
GO:0009791 post-embryonic development
GO:0030308 negative regulation of cell growth
GO:0042694 muscle cell fate specification
GO:0048747 muscle fiber development
GO:0055003 cardiac myofibril assembly
GO:0055010 ventricular cardiac muscle tissue morphogenesis
GO:0060047 heart contraction
GO:0060048 cardiac muscle contraction
Cellular Component
GO:0005856 cytoskeleton
GO:0015629 actin cytoskeleton
GO:0016459 myosin complex
GO:0030016 myofibril
GO:0031672 A band
Protein Structure and Domains
PDB ID MGI:97272
InterPro IPR002048 EF-hand domain
PFAM PF00036
PF13202
PF13405
PRINTS
PIRSF
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P51667
PhosphoSite PhosphoSite-P51667
TrEMBL Q9EQ12
UniProt Splice Variant
Entrez Gene 17906
UniGene
RefSeq NP_034991
MGI ID
MGI Symbol Myl2
OMIM
CCDS CCDS39252
HPRD
IMGT
EMBL AC140353 AF302688 AK002367 AK146674 BC061144 M91602
GenPept AAA39796 AAG40240 AAH61144 BAB22045 BAE27350

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca