Mus musculus Protein: Dgka | |||||||||||||
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Summary | |||||||||||||
InnateDB Protein | IDBP-198285.6 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | Dgka | ||||||||||||
Protein Name | diacylglycerol kinase, alpha | ||||||||||||
Synonyms | 80kDa; AW146112; Dagk1; | ||||||||||||
Species | Mus musculus | ||||||||||||
Ensembl Protein | ENSMUSP00000026414 | ||||||||||||
InnateDB Gene | IDBG-198283 (Dgka) | ||||||||||||
Protein Structure | |||||||||||||
UniProt Annotation | |||||||||||||
Function | Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity. {ECO:0000250}. | ||||||||||||
Subcellular Localization | |||||||||||||
Disease Associations | |||||||||||||
Tissue Specificity | |||||||||||||
Comments | |||||||||||||
Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||||
PDB ID | MGI:102952 | ||||||||||||
InterPro |
IPR000756
Diacylglycerol kinase, accessory domain IPR001206 Diacylglycerol kinase, catalytic domain IPR002048 EF-hand domain IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol binding |
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PFAM |
PF00609
PF00781 PF00036 PF13202 PF13405 PF00130 |
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PRINTS | |||||||||||||
PIRSF | |||||||||||||
SMART |
SM00045
SM00046 SM00054 SM00109 |
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TIGRFAMs | |||||||||||||
Post-translational Modifications | |||||||||||||
Modification | |||||||||||||
Cross-References | |||||||||||||
SwissProt | O88673 | ||||||||||||
PhosphoSite | PhosphoSite-O88673 | ||||||||||||
TrEMBL | |||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 13139 | ||||||||||||
UniGene | Mm.291235 | ||||||||||||
RefSeq | NP_058091 | ||||||||||||
MGI ID | |||||||||||||
MGI Symbol | Dgka | ||||||||||||
OMIM | |||||||||||||
CCDS | CCDS24290 | ||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
EMBL | AF085219 BC006713 | ||||||||||||
GenPept | AAC33483 AAH06713 | ||||||||||||