InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tsr1

Summary

InnateDB Protein

IDBP-199303.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tsr1

Protein Name

TSR1, 20S rRNA accumulation, homolog (yeast)

Synonyms

AU040765; AW550801; mKIAA1401;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000039027

InnateDB Gene

IDBG-199301 (Tsr1)

Protein Structure

UniProt Annotation

Function

Required during maturation of the 40S ribosomal subunit in the nucleolus. {ECO:0000250}.

Subcellular Localization

Nucleus, nucleolus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 38 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	38 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0044822	poly(A) RNA binding

Biological Process

GO:0008150	biological_process
GO:0042254	ribosome biogenesis
GO:0042255	ribosome assembly

Cellular Component

GO:0005575	cellular_component
GO:0005634	nucleus
GO:0005730	nucleolus

Protein Structure and Domains

PDB ID

MGI:2144566

InterPro

IPR007034 Ribosome biogenesis protein BMS1/TSR1, C-terminal
IPR009000 Translation protein, beta-barrel domain
IPR012948 AARP2CN

PFAM

PF04950
PF08142

PRINTS

PIRSF

SMART

SM00785

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q5SWD9

PhosphoSite

PhosphoSite-Q5SWD9

TrEMBL

UniProt Splice Variant

Entrez Gene

104662

UniGene

Mm.220843

RefSeq

NP_796299

MGI ID

MGI Symbol

Tsr1

OMIM

CCDS

CCDS36225

HPRD

IMGT

EMBL

AK030545 AK129350 AK134365 AK154063 AK162686 AK165662 AL604066 BC031531

GenPept

AAH31531 BAC98160 BAE20453 BAE22117 BAE32349 BAE37023 BAE38324 CAI24249