Mus musculus Protein: Ptgfr
Summary
InnateDB Protein IDBP-199874.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ptgfr
Protein Name prostaglandin F receptor
Synonyms AI957154; fp; PGF;
Species Mus musculus
Ensembl Protein ENSMUSP00000029670
InnateDB Gene IDBG-199872 (Ptgfr)
Protein Structure
UniProt Annotation
Function Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum (By similarity). {ECO:0000250}.
Subcellular Localization Cell membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004958 prostaglandin F receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0032496 response to lipopolysaccharide
GO:0035584 calcium-mediated signaling using intracellular calcium source
GO:0043066 negative regulation of apoptotic process
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:97796
InterPro IPR000141 Prostaglandin F receptor
IPR000276 G protein-coupled receptor, rhodopsin-like
IPR001105 Thromboxane receptor
IPR001244 Prostaglandin DP receptor
IPR008365 Prostanoid receptor
IPR017452 GPCR, rhodopsin-like, 7TM
PFAM PF00001
PRINTS PR00855
PR00237
PR00429
PR00428
PR01788
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P43117
PhosphoSite PhosphoSite-
TrEMBL Q8BNT7
UniProt Splice Variant
Entrez Gene 19220
UniGene Mm.331442
RefSeq NP_032992
MGI ID
MGI Symbol Ptgfr
OMIM
CCDS CCDS17913
HPRD
IMGT
EMBL AB073966 AB094411 AK080620 AK087833 AK141760 BC064794 CH466532 D17433
GenPept AAH64794 BAA04251 BAC37962 BAC40021 BAC80245 BAC80246 BAE24824 EDL11940 EDL11941