InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ndufaf3

Summary

InnateDB Protein

IDBP-200222.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ndufaf3

Protein Name

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3

Synonyms

4733401H18Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000073832

InnateDB Gene

IDBG-200220 (Ndufaf3)

Protein Structure

UniProt Annotation

Function

Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}. Mitochondrion inner membrane {ECO:0000250}.

Disease Associations

Tissue Specificity

Strongly expressed in testis and weakly expressed in the epididymis. Expressed in spermatocytes. {ECO:0000269PubMed:12653254}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0032981

mitochondrial respiratory chain complex I assembly

Cellular Component

GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane

Protein Structure and Domains

PDB ID

MGI:1913956

InterPro

IPR007523 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3

PFAM

PF04430

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9JKL4

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

66706

UniGene

Mm.29471

RefSeq

NP_075736

MGI ID

MGI Symbol

Ndufaf3

OMIM

CCDS

CCDS23531

HPRD

IMGT

EMBL

AF235017 AK005252 AK014634 BC027513

GenPept

AAF61723 AAH27513 BAB23907 BAB29477