Version 5.4
Mus musculus Gene: Ndufaf3
Summary
InnateDB Gene IDBG-200220.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ndufaf3
Gene Name NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
Synonyms 4733401H18Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000070283
Encoded Proteins
IDBP-200222
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000178057:
This gene encodes a mitochondrial complex I assembly protein that interacts with complex I subunits. Mutations in this gene cause mitochondrial complex I deficiency, a fatal neonatal disorder of the oxidative phosphorylation system. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:108565866-108567342
Strand Reverse strand
Band F2
Transcripts
ENSMUST00000074208 ENSMUSP00000073832
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0032981 mitochondrial respiratory chain complex I assembly
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000178057
View Gene Order
ENSBTAG00000018918
Not yet available
Cross-References
SwissProt Q9JKL4
TrEMBL
UniProt Splice Variant
Entrez Gene 66706
UniGene Mm.29471
RefSeq NM_023247
OMIM
CCDS CCDS23531
HPRD
IMGT
MGI ID MGI:1913956
MGI Symbol Ndufaf3
EMBL AF235017 AK005252 AK014634 BC027513
GenPept AAF61723 AAH27513 BAB23907 BAB29477
RNA Seq Atlas 66706

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca