InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gnpat

Summary

InnateDB Protein

IDBP-200474.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gnpat

Protein Name

glyceronephosphate O-acyltransferase

Synonyms

AU019525; D1Ertd819e; DHAPAT;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000034466

InnateDB Gene

IDBG-200472 (Gnpat)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Peroxisome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}. Note=Exclusively localized to the lumenal side of the peroxisomal membrane. {ECO:0000250}.

Disease Associations

Tissue Specificity

Highly expressed in liver and testis. Lower levels in heart, brain, lung and kidney. Detected in spleen.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0005102	receptor binding
GO:0005515	protein binding
GO:0016287	glycerone-phosphate O-acyltransferase activity
GO:0016290	palmitoyl-CoA hydrolase activity
GO:0016746	transferase activity, transferring acyl groups

Biological Process

GO:0006650	glycerophospholipid metabolic process
GO:0007416	synapse assembly
GO:0007584	response to nutrient
GO:0008152	metabolic process
GO:0008611	ether lipid biosynthetic process
GO:0021587	cerebellum morphogenesis
GO:0030913	paranodal junction assembly
GO:0042493	response to drug
GO:0042552	myelination
GO:0042594	response to starvation
GO:0061024	membrane organization
GO:0070542	response to fatty acid