Version 5.4
Mus musculus Gene: Gnpat
Summary
InnateDB Gene IDBG-200472.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gnpat
Gene Name glyceronephosphate O-acyltransferase
Synonyms AU019525; D1Ertd819e; DHAPAT
Species Mus musculus
Ensembl Gene ENSMUSG00000031985
Encoded Proteins
IDBP-200474
glyceronephosphate O-acyltransferase
IDBP-542741
glyceronephosphate O-acyltransferase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116906:
This gene encodes an enzyme located in the peroxisomal membrane which is essential to the synthesis of ether phospholipids. Mutations in this gene are associated with rhizomelic chondrodysplasia punctata. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:124863033-124890057
Strand Forward strand
Band E2
Transcripts
ENSMUST00000034466 ENSMUSP00000034466
ENSMUST00000161986 ENSMUSP00000125323
ENSMUST00000162455
ENSMUST00000161628
ENSMUST00000162192
ENSMUST00000159864
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0005102 receptor binding
GO:0005515 protein binding
GO:0016287 glycerone-phosphate O-acyltransferase activity
GO:0016290 palmitoyl-CoA hydrolase activity
GO:0016746 transferase activity, transferring acyl groups
Biological Process
GO:0006650 glycerophospholipid metabolic process
GO:0007416 synapse assembly
GO:0007584 response to nutrient
GO:0008152 metabolic process
GO:0008611 ether lipid biosynthetic process
GO:0021587 cerebellum morphogenesis
GO:0030913 paranodal junction assembly
GO:0042493 response to drug
GO:0042552 myelination
GO:0042594 response to starvation
GO:0061024 membrane organization
GO:0070542 response to fatty acid
Cellular Component
GO:0005739 mitochondrion
GO:0005777 peroxisome
GO:0005778 peroxisomal membrane
GO:0005782 peroxisomal matrix
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000116906
View Gene Order
ENSBTAG00000010773
Not yet available
Pathways
NETPATH
REACTOME
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_258151
Plasmalogen biosynthesis pathway
REACT_246750
Peroxisomal lipid metabolism pathway
REACT_188641
Glycerophospholipid biosynthesis pathway
REACT_188640
Synthesis of PA pathway
REACT_188643
Phospholipid metabolism pathway
KEGG
mmu00564
Glycerophospholipid metabolism pathway
mmu04146
Peroxisome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_1407
Plasmalogen biosynthesis pathway
REACT_120906
Synthesis of PA pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_16957
Peroxisomal lipid metabolism pathway
REACT_121401
Glycerophospholipid biosynthesis pathway
REACT_120870
Phospholipid metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa00564
Glycerophospholipid metabolism pathway
hsa04146
Peroxisome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.29114
RefSeq NM_010322
OMIM
CCDS CCDS22776
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca