InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Setd8

Summary

InnateDB Protein

IDBP-200662.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Setd8

Protein Name

SET domain containing (lysine methyltransferase) 8

Synonyms

2410195B05Rik; AA617402; AW536475; PR-SET7;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000052953

InnateDB Gene

IDBG-200660 (Setd8)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	0
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	19 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002039	p53 binding
GO:0003714	transcription corepressor activity
GO:0005515	protein binding
GO:0016279	protein-lysine N-methyltransferase activity
GO:0018024	histone-lysine N-methyltransferase activity

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0018026	peptidyl-lysine monomethylation
GO:0034968	histone lysine methylation
GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator
GO:0045892	negative regulation of transcription, DNA-templated