InnateDB Protein
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IDBP-201054.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Shisa5
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Protein Name
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shisa homolog 5 (Xenopus laevis)
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Synonyms
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2310008D10Rik; 6430628I05Rik; mShisa5; Scotin;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000026737
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InnateDB Gene
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IDBG-201052 (Shisa5)
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Protein Structure
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Function |
Can induce apoptosis in a caspase-dependent manner and plays a role in p53/TP53-dependent apoptosis. {ECO:0000269PubMed:12135983}.
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Subcellular Localization |
Endoplasmic reticulum membrane {ECO:0000269PubMed:12135983}; Single-pass type I membrane protein {ECO:0000269PubMed:12135983}. Nucleus membrane {ECO:0000269PubMed:12135983}.
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Disease Associations |
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Tissue Specificity |
Spleen and thymus.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated |
Total |
2
[view]
|
Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
1
[view]
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
4 [view]
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|
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Molecular Function |
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Biological Process |
GO:0042771
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intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
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GO:0043123
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positive regulation of I-kappaB kinase/NF-kappaB signaling
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GO:0072332
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intrinsic apoptotic signaling pathway by p53 class mediator
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Cellular Component |
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PDB ID |
MGI:1915044
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9D7I0
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PhosphoSite |
PhosphoSite-Q9D7I0
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TrEMBL |
G3UWC7
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UniProt Splice Variant |
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Entrez Gene |
66940
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UniGene |
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RefSeq |
NP_080134
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MGI ID |
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MGI Symbol |
Shisa5
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OMIM |
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CCDS |
CCDS23543
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HPRD |
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IMGT |
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EMBL |
AC140383
AF520699
AH011687
AK009225
AK018291
AK020877
AK033545
AK045368
AK081060
AK090357
AK090373
BC010238
BC017600
BC057089
CH466560
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GenPept |
AAH10238
AAH17600
AAH57089
AAM74233
AAM74234
BAB26148
BAB31149
BAB32237
BAC28350
BAC32331
BAC38125
BAC41183
BAC41188
EDL21330
EDL21331
EDL21336
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