InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ptger3

Summary

InnateDB Protein

IDBP-201072.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ptger3

Protein Name

prostaglandin E receptor 3 (subtype EP3)

Synonyms

EP3; Pgerep3; Ptgerep3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000043302

InnateDB Gene

IDBG-201070 (Ptger3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0004957	prostaglandin E receptor activity
GO:0005515	protein binding

Biological Process

GO:0001660	fever generation
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204	positive regulation of cytosolic calcium ion concentration
GO:0015701	bicarbonate transport
GO:0032496	response to lipopolysaccharide
GO:0035810	positive regulation of urine volume

Cellular Component

GO:0005886	plasma membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:97795

InterPro

IPR000154 Prostanoid EP3 receptor type 3
IPR000265 Prostanoid EP3 receptor
IPR000276 G protein-coupled receptor, rhodopsin-like
IPR001105 Thromboxane receptor
IPR001244 Prostaglandin DP receptor
IPR008365 Prostanoid receptor
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019420 7TM GPCR, serpentine receptor class bc (Srbc)

PFAM

PF00001
PF10316

PRINTS

PR00585
PR00582
PR00237
PR00429
PR00428
PR01788

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite