InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rc3h1

Summary

InnateDB Protein

IDBP-201253.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rc3h1

Protein Name

RING CCCH (C3H) domains 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000037178

InnateDB Gene

IDBG-201251 (Rc3h1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	18 [view]
Protein-Protein	13 [view]
Protein-DNA	0
Protein-RNA	5 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003729	mRNA binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0046872	metal ion binding

Biological Process

GO:0001782	B cell homeostasis
GO:0010468	regulation of gene expression
GO:0010608	posttranscriptional regulation of gene expression
GO:0042098	T cell proliferation
GO:0043029	T cell homeostasis
GO:0045623	negative regulation of T-helper cell differentiation
GO:0048535	lymph node development
GO:0048536	spleen development
GO:0061470	T follicular helper cell differentiation
GO:1901224	positive regulation of NIK/NF-kappaB signaling

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

MGI:2685397

InterPro

IPR000571 Zinc finger, CCCH-type
IPR001841 Zinc finger, RING-type

PFAM

PF00642
PF13639
PF14634

PRINTS

PIRSF

SMART

SM00356
SM00184

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

H7BX02

UniProt Splice Variant

Entrez Gene

381305

UniGene

Mm.415346

RefSeq

MGI ID

MGI Symbol

Rc3h1

OMIM

CCDS

HPRD

IMGT

EMBL

AC119204

GenPept