InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Slc15a4

Summary

InnateDB Protein

IDBP-201522.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc15a4

Protein Name

solute carrier family 15, member 4

Synonyms

AA987064; AW742963; C130069N12Rik; PHT1; PTR4;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000031367

InnateDB Gene

IDBG-201520 (Slc15a4)

Protein Structure

UniProt Annotation

Function

Proton oligopeptide cotransporter. Transports free histidine and certain di- and tripeptides (By similarity). {ECO:0000250}.

Subcellular Localization

Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0005290	L-histidine transmembrane transporter activity
GO:0015293	symporter activity

Biological Process

GO:0006810	transport
GO:0006857	oligopeptide transport
GO:0015031	protein transport
GO:0015817	histidine transport
GO:0045087	innate immune response (InnateDB)
GO:0055085	transmembrane transport

Cellular Component

GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:2140796

InterPro

IPR000109 Proton-dependent oligopeptide transporter family
IPR011701 Major facilitator superfamily
IPR016196 Major facilitator superfamily domain, general substrate transporter

PFAM

PF00854
PF07690

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q91W98

PhosphoSite