InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tefm

Summary

InnateDB Protein

IDBP-203952.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tefm

Protein Name

RIKEN cDNA 1110002N22 gene

Synonyms

1110002N22Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000059304

InnateDB Gene

IDBG-203950 (Tefm)

Protein Structure

UniProt Annotation

Function

Transcription elongation factor which increases mitochondrial RNA polymerase processivity. Regulates transcription of the mitochondrial genome, including genes important for the oxidative phosphorylation machinery (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion matrix {ECO:0000250}. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0005515	protein binding
GO:0030337	DNA polymerase processivity factor activity
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006119	oxidative phosphorylation
GO:0006259	DNA metabolic process
GO:0006355	regulation of transcription, DNA-templated
GO:0006390	transcription from mitochondrial promoter