InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cd48

Summary

InnateDB Protein

IDBP-204795.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cd48

Protein Name

CD48 antigen

Synonyms

AI449234; AW610730; Bcm-1; BCM1; BLAST; BLAST-1; BLAST1; MEM-102; Sgp-60; SLAMF2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000064241

InnateDB Gene

IDBG-204791 (Cd48)

Protein Structure

UniProt Annotation

Function

Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation.

Subcellular Localization

Cell membrane; Lipid-anchor, GPI-anchor.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003823	antigen binding
GO:0004872	receptor activity
GO:0005515	protein binding

Biological Process

GO:0007165	signal transduction
GO:0042110	T cell activation
GO:0045576	mast cell activation

Cellular Component

GO:0005886	plasma membrane
GO:0009897	external side of plasma membrane
GO:0016021	integral component of membrane
GO:0043234	protein complex
GO:0045121	membrane raft
GO:0046658	anchored component of plasma membrane

Protein Structure and Domains

PDB ID

MGI:88339

InterPro

IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
IPR013151 Immunoglobulin

PFAM

PF07679
PF07686
PF00047

PRINTS

PIRSF

SMART

SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P18181