Version 5.4
Mus musculus Protein: Cort
Summary
InnateDB Protein IDBP-204923.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cort
Protein Name cortistatin
Synonyms CST; PCST;
Species Mus musculus
Ensembl Protein ENSMUSP00000030815
InnateDB Gene IDBG-204921 (Cort)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity Expressed in a subset of GABAergic cells in the cortex and hippocampus.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001664 G-protein coupled receptor binding
GO:0005179 hormone activity
GO:0005184 neuropeptide hormone activity
Biological Process
GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID MGI:109538
InterPro IPR018142 Somatostatin/Cortistatin, C-terminal
PFAM PF03002
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P56469
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 12854
UniGene
RefSeq NP_031771
MGI ID
MGI Symbol Cort
OMIM
CCDS CCDS18953
HPRD
IMGT
EMBL AF013253 AF050156 AK013496 AL731655
GenPept AAB66896 AAD51127 BAB28882 CAM18589

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca