Version 5.4
| Mus musculus Gene: Cort | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Summary | |||||||||
| InnateDB Gene | IDBG-204921.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Cort | ||||||||
| Gene Name | cortistatin | ||||||||
| Synonyms | CST; PCST | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000028971 | ||||||||
| Encoded Proteins |
cortistatin
|
||||||||
| Protein Structure |
|
||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000241563:
This gene encodes a neuropeptide that is structurally similar to somatostatin. It binds to all known somatostatin receptors, and shares many pharmacological and functional properties with somatostatin, including the depression of neuronal activity. However, it also has many properties distinct from somatostatin, such as induction of slow-wave sleep, apparently by antagonism of the excitatory effects of acetylcholine on the cortex, reduction of locomotor activity, and activation of cation selective currents not responsive to somatostatin. The preproprotein undergoes further processing into multiple mature products. Read-through transcripts exist between this gene and the upstream APITD1 (apoptosis-inducing, TAF9-like domain 1) gene, as represented in GeneID:100526739. [provided by RefSeq, Nov 2010] |
||||||||
| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 4:149125034-149126763 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | E2 | ||||||||
| Transcripts |
|
||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
|
||||||||
| Gene Ontology | |||||||||
Molecular Function |
|
||||||||
| Biological Process |
|
||||||||
| Cellular Component |
|
||||||||
| Orthologs | |||||||||
|
Species
Homo sapiens
Bos taurus
|
Gene ID
Gene Order
Not yet available
|
||||||||
| Cross-References | |||||||||
| SwissProt | P56469 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 12854 | ||||||||
| UniGene | |||||||||
| RefSeq | NM_007745 XM_006538516 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS18953 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:109538 | ||||||||
| MGI Symbol | Cort | ||||||||
| EMBL | AF013253 AF050156 AK013496 AL731655 | ||||||||
| GenPept | AAB66896 AAD51127 BAB28882 CAM18589 | ||||||||
| RNA Seq Atlas | 12854 | ||||||||