InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ccbp2

Summary

InnateDB Protein

IDBP-205743.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ccbp2

Protein Name

chemokine binding protein 2

Synonyms

AI464239; Ccbp2; CCR10; CCR9; Cmkbr9; D6;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000050119

InnateDB Gene

IDBG-205741 (Ccbp2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0005044	scavenger receptor activity
GO:0005515	protein binding
GO:0016493	C-C chemokine receptor activity
GO:0016494	C-X-C chemokine receptor activity
GO:0019957	C-C chemokine binding

Biological Process

GO:0006898	receptor-mediated endocytosis
GO:0006935	chemotaxis
GO:0006954	inflammatory response
GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0042119	neutrophil activation
GO:0045087	innate immune response (InnateDB)
GO:0070098	chemokine-mediated signaling pathway

Cellular Component

GO:0005769	early endosome
GO:0005884	actin filament
GO:0005886	plasma membrane
GO:0016021	integral component of membrane
GO:0055037	recycling endosome

Protein Structure and Domains

PDB ID

MGI:1891697

InterPro

IPR000248 Angiotensin II receptor family
IPR000276 G protein-coupled receptor, rhodopsin-like
IPR000355 Chemokine receptor family
IPR001277 CXC chemokine receptor 4
IPR017452 GPCR, rhodopsin-like, 7TM

PFAM

PF00001

PRINTS

PR00241
PR00237
PR00657
PR00645

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O08707